DOCITEREN

This brand name is authorized in Germany

Active ingredients

The drug DOCITEREN contains a combination of these active pharmaceutical ingredients (APIs):

1 Propranolol
UNII F8A3652H1V - PROPRANOLOL HYDROCHLORIDE

Propranolol is a competitive antagonist at both beta, and beta2-adrenoceptor, but has membrane stabilising activity at concentrations exceeding 1-3mg/litre, though such concentrations are rarely achieved during oral therapy. Competitive beta-blockade has been demonstrated in man by a parallel shift to the right in the dose-heart rate response curve to beta-agonists such as isoprenaline.

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2 Triamterene
UNII WS821Z52LQ - TRIAMTERENE

Triamterene is a potassium-sparing agent. Triamterene inhibits the reabsorption of sodium ions in exchange for potassium and hydrogen ions at that segment of the distal tubule under the control of adrenal mineralocorticoids (especially aldosterone). The fraction of filtered sodium reaching this distal tubular exchange site is relatively small, and the amount which is exchanged depends on the level of mineralocorticoid activity. Thus, the degree of natriuresis and diuresis produced by inhibition of the exchange mechanism is necessarily limited.

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3 Hydrochlorothiazide
UNII 0J48LPH2TH - HYDROCHLOROTHIAZIDE

Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted.

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Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C07DA Beta blocking agents, non-selective, thiazides and other diuretics C Cardiovascular system → C07 Beta blocking agents → C07D Beta blocking agents, thiazides and other diuretics
Discover more medicines within C07DA

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: DE Bundesinstitut fĂźr Arzneimittel und Medizinprodukte Identifier(s): 02150904

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