Chemical formula: C₁₂H₁₁N₇ Molecular mass: 253.263 g/mol PubChem compound: 5546
Triamterene is a potassium-sparing agent. Triamterene inhibits the reabsorption of sodium ions in exchange for potassium and hydrogen ions at that segment of the distal tubule under the control of adrenal mineralocorticoids (especially aldosterone). The fraction of filtered sodium reaching this distal tubular exchange site is relatively small, and the amount which is exchanged depends on the level of mineralocorticoid activity. Thus, the degree of natriuresis and diuresis produced by inhibition of the exchange mechanism is necessarily limited.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03DB02 | Triamterene | C Cardiovascular system → C03 Diuretics → C03D Potassium-sparing agents → C03DB Other potassium-sparing agents |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DYRENIUM Capsule | FDA, National Drug Code (US) | MPI, US: SPL/Old |
Triamterene is an active ingredient of these brands:
Austria (AT)
Finland (FI)
France (FR)
Germany (DE)
Japan (JP)Spain (ES)
Tunisia (TN)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
