DUODOPA

This brand name is authorized in Australia, Austria, Canada, Croatia, Cyprus, Estonia, Finland, France, Ireland, Israel, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, South Africa, Spain, Turkey, UK.

Active ingredients

The drug DUODOPA contains a combination of these active pharmaceutical ingredients (APIs):

1
UNII 46627O600J - LEVODOPA
 

According to the current understanding, the symptoms of Parkinson’s disease are related to depletion of dopamine in the corpus striatum. Dopamine does not cross the blood-brain barrier. Levodopa, the precursor of dopamine, crosses the blood brain barrier and relieves the symptoms of the disease.

 
Read more about Levodopa
2
UNII MNX7R8C5VO - CARBIDOPA
 

Carbidopa is a peripheral aromatic amino acid decarboxylase inhibitor. It prevents metabolism of levodopa to dopamine in the peripheral circulation, ensuring that a higher proportion of the dose reaches the brain, where dopamine exerts its therapeutic effects. A lower dose of levodopa can be used when it is coadministered with carbidopa, reducing the incidence and severity of peripheral side effects.

 
Read more about Carbidopa

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group Classification
N04BA02 Levodopa and decarboxylase inhibitor N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BA Dopa and dopa derivatives
Discover more medicines within N04BA02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
AU Pharmaceutical Benefits Scheme 11910W, 11913B, 11919H, 8970D, 9743T, 9744W
CA Health Products and Food Branch 02292165
EE Ravimiamet 1192867
ES Centro de información online de medicamentos de la AEMPS 66547
FI Lääkealan turvallisuus- ja kehittämiskeskus 095314
FR Base de données publique des médicaments 64757532
GB Medicines & Healthcare Products Regulatory Agency 101620
HR Agencija za lijekove i medicinske proizvode HR-H-753613005
IE Health Products Regulatory Authority 89058
IL מִשְׂרַד הַבְּרִיאוּת 6662
JP 医薬品医療機器総合機構 1169101S1020
LT Valstybinė vaistų kontrolės tarnyba 1021102
NL Z-Index G-Standaard, PRK 77569
NZ Medicines and Medical Devices Safety Authority 16907
PL Rejestru Produktów Leczniczych 100150430
RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale W60962001
TR İlaç ve Tıbbi Cihaz Kurumu 8680656080063
ZA Health Products Regulatory Authority 44/5.4.1/0456

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