Carbidopa

Chemical formula: C₁₀H₁₄N₂O₄  Molecular mass: 226.229 g/mol  PubChem compound: 34359

Active ingredient description

Carbidopa is a peripheral aromatic amino acid decarboxylase inhibitor. It prevents metabolism of levodopa to dopamine in the peripheral circulation, ensuring that a higher proportion of the dose reaches the brain, where dopamine exerts its therapeutic effects. A lower dose of levodopa can be used when it is coadministered with carbidopa, reducing the incidence and severity of peripheral side effects.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
V03AX Other therapeutic products V Various → V03 All other therapeutic products → V03A All other therapeutic products
Discover more medicines within V03AX

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 28860-95-9
CAS Substance: 38821-49-7
DrugBank Drug: DB00190
KEGG Drug: D00558
PubChem Compound: 34359
SNOMED-CT Concept: 73579000
Carbidopa (substance)
UNII Identifier: MNX7R8C5VO
CARBIDOPA

Medicines

Carbidopa is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

  • (combination) DUODOPA
  • (combination) ISICOM as Carbidopa monohydrate
  • (combination) LECIGON as Carbidopa monohydrate
  • (combination) PRODUODOPA as FOSCARBIDOPA
  • (combination) TRIGELAN as Carbidopa monohydrate

Singapore (SG)

South Africa (ZA)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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