This brand name is authorized in Estonia, Lithuania, Poland
The drug DUZALLO contains a combination of these active pharmaceutical ingredients (APIs):
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1
Allopurinol
UNII 63CZ7GJN5I - ALLOPURINOL
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Allopurinol is a xanthine-oxidase inhibitor. Allopurinol and its main metabolite oxipurinol lower the level of uric acid in plasma and urine by inhibition of xanthine oxidase, the enzyme catalyzing the oxidation of hypoxanthine to xanthine and xanthine to uric acid. |
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2
Lesinurad
UNII 09ERP08I3W - LESINURAD
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Lesinurad is a selective uric acid reabsorption inhibitor that inhibits uric acid transporter URAT1. URAT1 is responsible for the majority of the reabsorption of filtered uric acid from the renal tubular lumen. By inhibiting URAT1, lesinurad increases uric acid excretion and thereby lowers serum uric acid (sUA). Lesinurad also inhibits OAT4, a uric acid transporter involved in diuretic-induced hyperuricaemia. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M04AA51 | Allopurinol, combinations | M Musculo-skeletal system → M04 Antigout preparations → M04A Antigout preparations → M04AA Preparations inhibiting uric acid production |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1778407, 1778418 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1086083, 1086084, 1086085, 1086086, 1088582, 1088583 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100410640, 100410657 |
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