This brand name is authorized in United States. It is also authorized in Austria, Brazil, Croatia, Estonia, Finland, Hong Kong SAR China, Ireland, Israel, Japan, Lithuania, Netherlands, Poland, Spain, UK.
The drug EMPLICITI contains one active pharmaceutical ingredient (API):
1
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UNII
1351PE5UGS - ELOTUZUMAB
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Elotuzumab is an immunostimulatory humanised, IgG1 monoclonal antibody that specifically targets the SLAMF7 (signaling lymphocyte activation molecule family member 7) protein. Elotuzumab directly activates natural killer cells through both the SLAMF7 pathway and Fc receptors enhancing anti-myeloma activity in vitro. Elotuzumab also targets SLAMF7 on myeloma cells and through interactions with Fc receptors on specific immune cells, promotes the killing of myeloma cells through NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC) and macrophage-mediated antibody-dependant cellular phagocytosis (ADCP). |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| EMPLICITI Powder for concentrate for solution for infusion | MPI, EU: SmPC | European Medicines Agency (EU) |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| L01FX08 | Elotuzumab | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01F Monoclonal antibodies and antibody drug conjugates → L01FX Other monoclonal antibodies |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| BR | Câmara de Regulação do Mercado de Medicamentos | 505118040022902, 505118040023002 |
| EE | Ravimiamet | 1718377, 1718388 |
| ES | Centro de información online de medicamentos de la AEMPS | 1161088002 |
| FI | Lääkealan turvallisuus- ja kehittämiskeskus | 057220, 511556 |
| GB | Medicines & Healthcare Products Regulatory Agency | 328172, 328177 |
| HK | Department of Health Drug Office | 64832, 64833 |
| IL | מִשְׂרַד הַבְּרִיאוּת | 7814, 7815 |
| JP | 医薬品医療機器総合機構 | 4291434D1020, 4291434D2027 |
| LT | Valstybinė vaistų kontrolės tarnyba | 1080362, 1080363 |
| NL | Z-Index G-Standaard, PRK | 136395, 136409 |
| PL | Rejestru Produktów Leczniczych | 100366092, 100366117 |
| US | FDA, National Drug Code | 0003-2291, 0003-4522 |
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