This brand name is authorized in Austria, Estonia, Ireland, Italy, Lithuania, Poland, Spain.
The drug GLUBRAVA contains a combination of these active pharmaceutical ingredients (APIs):
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UNII
JQT35NPK6C - PIOGLITAZONE HYDROCHLORIDE
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Pioglitazone effects may be mediated by a reduction of insulin resistance. Pioglitazone appears to act via activation of specific nuclear receptors (peroxisome proliferator activated receptor gamma) leading to increased insulin sensitivity of liver, fat and skeletal muscle cells in animals. Treatment with pioglitazone has been shown to reduce hepatic glucose output and to increase peripheral glucose disposal in the case of insulin resistance. |
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UNII
786Z46389E - METFORMIN HYDROCHLORIDE
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Metformin is a biguanide with antihyperglycaemic effects, lowering both basal and postprandial plasma glucose. It does not stimulate insulin secretion and therefore does not produce hypoglycaemia. |
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This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| A10BD05 | Metformin and pioglitazone | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BD Combinations of oral blood glucose lowering drugs |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| EE | Ravimiamet | 1364374, 1364385, 1364396, 1364408, 1364419, 1364420, 1364431, 1364442, 1364453 |
| ES | Centro de información online de medicamentos de la AEMPS | 07421005 |
| IT | Agenzia del Farmaco | 038529057 |
| LT | Valstybinė vaistų kontrolės tarnyba | 1032543, 1032544, 1032545, 1032546, 1032547, 1032548, 1032549, 1032550, 1032551 |
| PL | Rejestru Produktów Leczniczych | 100309869 |
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