HUMIRA

This brand name is authorized in Australia, Austria, Brazil, Canada, Croatia, Cyprus, Ecuador, Estonia, Finland, France, Germany, Hong Kong SAR China, Ireland, Israel, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, South Africa, Spain, Tunisia, Turkey, UK.

Active ingredients

The drug HUMIRA contains one active pharmaceutical ingredient (API):

1	Adalimumab UNII FYS6T7F842 - ADALIMUMAB
	Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors. Adalimumab also modulates biological responses that are induced or regulated by TNF, including changes in the levels of adhesion molecules responsible for leukocyte migration (ELAM-1, VCAM-1, and ICAM-1 with an IC50 of 0.1-0.2 nM).
	Read more about Adalimumab

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
HUMIRA 40mg/0.4ml Solution for injection in pre-filled syringe / pen	MPI, EU: SmPC	European Medicines Agency (EU)
HUMIRA 40mg/0.8ml Solution for injection in pre-filled syringe / pen	MPI, EU: SmPC	European Medicines Agency (EU)
HUMIRA 20mg Solution for injection in pre-filled syringe	MPI, EU: SmPC	European Medicines Agency (EU)
HUMIRA 80mg Solution for injection in pre-filled syringe / pen	MPI, EU: SmPC	European Medicines Agency (EU)
HUMIRA 40mg/0.8ml Solution for injection	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L04AB04	Adalimumab	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AB Tumor necrosis factor alpha (TNF-α) inhibitors
Discover more medicines within L04AB04

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	12335F, 12336G, 12337H, 12338J, 12339K, 12340L, 12341M, 12342N, 12343P, 12344Q, 12345R, 12346T, 12347W, 12358K, 12359L, 12360M, 12361N, 12362P, 12363Q, 12364R, 12371D, 12372E, 12373F, 12374G, 12375H, 12376J, 12377K, 12378L, 12379M, 12380N, 12381P, 12382Q, 12383R, 12389C, 12390D, 12391E, 12392F, 12393G, 12394H, 12395J, 12396K, 12397L, 12398M, 12399N, 12400P, 12404W, 12405X, 12406Y, 12407B, 12408C, 12409D, 12410E, 12411F, 12412G, 12413H, 12414J, 12418N, 12419P, 12421R, 12422T, 12423W, 12424X, 12425Y, 12426B, 12427C, 12428D, 12429E, 12430F, 12431G, 12432H, 12433J, 12441T, 12442W, 12443X, 12444Y, 12445B, 12446C, 12447D, 12448E, 12449F, 12450G, 12451H, 12452J, 12453K, 12454L, 12455M, 12524E
BR	Câmara de Regulação do Mercado de Medicamentos	543715100001817, 543715100001917, 543715110002403, 543718020002703, 543718020002803, 543718020002903, 543718020003003, 543718020003103, 543718020003203, 543718050003403
CA	Health Products and Food Branch	02258595, 02474263
DE	Bundesinstitut für Arzneimittel und Medizinprodukte	07764249, 07764255, 09635639, 09635645, 09635651, 09635668, 09635674, 11515233, 11515256, 11515262, 11515279, 12449716, 12468398, 12468406, 12468412, 12468429, 12470550, 12470573, 12471383, 12471408, 12471414, 12472052, 12472075, 12472081, 12472566, 12472572, 12472589, 12472595, 12473577, 12473583, 12473608, 12473614, 12478072, 12478089, 12478103, 12478126, 12504728, 12504734, 12504740, 12504757, 12529912, 12529929, 12562051, 12562068, 12562105, 12562140, 12580959, 12580971, 12580988, 12580994, 12589914, 12700978, 12701392, 12728646, 13248026, 13248032, 13516886, 13625233, 13625256, 13904453, 13946339, 13946345, 14032570, 14062364, 14139983, 14140012, 14168660, 14172207, 14172213, 14227256, 14227262, 14241285, 14257530, 14277426, 14277432, 14288826, 14289671, 14293709, 14299416, 14299422, 14304749, 14309072, 14309089, 14324083, 14366905, 14372484, 15201224, 15241413, 15375183, 15375208, 15375214, 15398669, 15398675, 15434075, 15619521, 15619857, 15619863, 15619886, 15619892, 15619900, 15625651, 15996614, 16586189, 16666190, 16743849, 16743884, 16743890, 16743921, 16789136, 16789165, 16789171, 16789188, 16840009, 16840015, 16868516, 16890504, 16890533, 17154813, 17312548
EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	108-MBE-0817, H5330613
EE	Ravimiamet	1199549, 1199550, 1199561, 1199572, 1205637, 1470316, 1470327, 1470473, 1470484, 1695089, 1695090, 1695102, 1695113, 1715240, 1715251, 1715262, 1715273, 1747267, 1752971, 1766662, 1796069
ES	Centro de información online de medicamentos de la AEMPS	103256013, 103256017, 103256021, 103256022
FI	Lääkealan turvallisuus- ja kehittämiskeskus	013544, 034685, 072770, 434559, 477362, 516783, 517641
FR	Base de données publique des médicaments	62975984, 64783769, 65325739, 69835440, 69847318
GB	Medicines & Healthcare Products Regulatory Agency	328818, 328822, 353154, 362437
HK	Department of Health Drug Office	65214, 65215, 67138
IE	Health Products Regulatory Authority	88565, 88570, 88879, 88892
IL	מִשְׂרַד הַבְּרִיאוּת	8028, 8515, 8561, 8968
JP	医薬品医療機器総合機構	3999426G3027, 3999426G4023, 3999426G5020, 3999426G6026, 3999426G7022
LT	Valstybinė vaistų kontrolės tarnyba	1028727, 1028728, 1028729, 1028730, 1028731, 1028732, 1028733, 1028734, 1028735, 1028736, 1078871, 1078872, 1078873, 1078874, 1079689, 1079690, 1079691, 1079692, 1082614, 1084333, 1084434, 1085960
NL	Z-Index G-Standaard, PRK	129771, 129798, 146153, 146781, 148822
NZ	Medicines and Medical Devices Safety Authority	10791, 12494, 14425, 18211, 18212, 20005, 20006, 20007
PL	Rejestru Produktów Leczniczych	100087630, 100362289, 100387183, 100396822
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W64674001, W64708001, W64709001, W64710001, W64711001
SG	Health Sciences Authority	12360P, 14626P, 15248P, 15718P, 15786P, 15787P
TN	Direction de la Pharmacie et du Médicament	15623011H, 16913031H
TR	İlaç ve Tıbbi Cihaz Kurumu	8680656080087, 8680656080285, 8680656080414, 8680656080421, 8680656080513
ZA	Health Products Regulatory Authority	37/30.2/0252