The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
L | Antineoplastic and immunomodulating agents | |
2
|
L04 | Immunosuppressants | |
3
|
L04A | Immunosuppressants | |
4
|
L04AB | Tumor necrosis factor alpha (TNF-α) inhibitors | |
5
|
L04AB04 | Adalimumab |
The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.
| Code | Route | Amount | Notes |
|---|---|---|---|
| PAREN | Parenteral | 2.9 mg |
| Active Ingredient |
|---|
|
Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors. Adalimumab also modulates biological responses that are induced or regulated by TNF, including changes in the levels of adhesion molecules responsible for leukocyte migration (ELAM-1, VCAM-1, and ICAM-1 with an IC50 of 0.1-0.2 nM). |
| Document | Type | Information Source | |
|---|---|---|---|
| HUKYNDRA 40mg Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) | |
| HUKYNDRA 80mg Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) | |
| HUMIRA 20mg Solution for injection in pre-filled syringe | MPI, EU: SmPC | European Medicines Agency (EU) | |
| HUMIRA 40mg/0.4ml Solution for injection in pre-filled syringe / pen | MPI, EU: SmPC | European Medicines Agency (EU) | |
| HUMIRA 40mg/0.8ml Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) | |
| HUMIRA 40mg/0.8ml Solution for injection in pre-filled syringe / pen | MPI, EU: SmPC | European Medicines Agency (EU) | |
| HUMIRA 80mg Solution for injection in pre-filled syringe / pen | MPI, EU: SmPC | European Medicines Agency (EU) | |
| IDACIO Solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| LIBMYRIS 40 mg Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) | |
| LIBMYRIS 80 mg Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) | |
| YUFLYMA 40 mg Solution for injection | MPI, EU: SmPC | European Medicines Agency (EU) |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.