This brand name is authorized in Australia, Brazil, Canada, Cyprus, Ecuador, Estonia, Hong Kong, Croatia, Ireland, Israel, Japan, Lithuania, Malta, Mexico, Netherlands, New Zealand, Poland, Romania, Singapore, Turkey, United Kingdom, United States, South Africa
The drug IMURAN contains one active pharmaceutical ingredient (API):
1
Azathioprine
UNII MRK240IY2L - AZATHIOPRINE
|
Azathioprine is a pro-drug of 6-mercaptopurine (6-MP). 6-MP is inactive but acts as a purine antagonist and requires cellular uptake and intracellular anabolism to thioguanine nucleotides (TGNs) for immunosuppression. The TGNs and other metabolites (e.g. 6-methyl-mecaptopurine ribonucleotides) inhibit de novo purine synthesis and purine nucleotide interconversions. |
Below package inserts are available for further reading:
Title | Information Source | Document Type | |
---|---|---|---|
IMURAN Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
L04AX01 | Azathioprine | L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AX Other immunosuppressants |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: AU | Pharmaceutical Benefits Scheme | Identifier(s): 2687K, 2688L |
Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 505612040035714, 505613110039803 |
Country: CA | Health Products and Food Branch | Identifier(s): 00004596, 02244895 |
Country: EC | Agencia Nacional de Regulación, Control y Vigilancia Sanitaria | Identifier(s): 29909-07-11 |
Country: EE | Ravimiamet | Identifier(s): 1004500, 1678158, 1865099 |
Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 20186, 20202, 27698, 381404 |
Country: HK | Department of Health Drug Office | Identifier(s): 03804, 30975 |
Country: HR | Agencija za lijekove i medicinske proizvode | Identifier(s): HR-H-628872163 |
Country: IE | Health Products Regulatory Authority | Identifier(s): 28762, 28847, 28894, 84612, 84625, 84638, 84662 |
Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 1107, 2457 |
Country: JP | 医薬品医療機器総合機構 | Identifier(s): 3999005F1059 |
Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1000951, 1085691, 1085796 |
Country: MT | Medicines Authority | Identifier(s): AA565/76001 |
Country: MX | Comisión Federal para la Protección contra Riesgos Sanitarios | Identifier(s): 69062 |
Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 5681 |
Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 16562, 337, 338 |
Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100030481, 100030498 |
Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W60846001 |
Country: SG | Health Sciences Authority | Identifier(s): 02082P |
Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8699874080090, 8699874080106 |
Country: US | FDA, National Drug Code | Identifier(s): 54766-590 |
Country: ZA | Health Products Regulatory Authority | Identifier(s): D/26/98 |
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