This brand name is authorized in Tunisia.
The drug ISOBAR contains a combination of these active pharmaceutical ingredients (APIs):
1
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UNII
L3H46UAC61 - METHYCLOTHIAZIDE
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2
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UNII
WS821Z52LQ - TRIAMTERENE
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Triamterene is a potassium-sparing agent. Triamterene inhibits the reabsorption of sodium ions in exchange for potassium and hydrogen ions at that segment of the distal tubule under the control of adrenal mineralocorticoids (especially aldosterone). The fraction of filtered sodium reaching this distal tubular exchange site is relatively small, and the amount which is exchanged depends on the level of mineralocorticoid activity. Thus, the degree of natriuresis and diuresis produced by inhibition of the exchange mechanism is necessarily limited. |
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This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| C03EA | Low-ceiling diuretics and potassium-sparing agents | C Cardiovascular system → C03 Diuretics → C03E Diuretics and potassium-sparing agents in combination |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| TN | Direction de la Pharmacie et du Médicament | 1263021, 9073131 |
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