ISTURISA

This brand name is authorized in Austria, Estonia, Finland, France, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Poland, Romania, United Kingdom, United States

Active ingredients

The drug ISTURISA contains one active pharmaceutical ingredient (API):

1 Osilodrostat UNII Y6581YAW9V - OSILODROSTAT PHOSPHATE

Osilodrostat is a cortisol synthesis inhibitor. It potently inhibits 11β-hydroxylase (CYP11B1), the enzyme responsible for the final step of cortisol biosynthesis in the adrenal gland. In Cushing’s disease, the fall in plasma cortisol concentration also stimulates ACTH secretion, via the feedback mechanism which accelerates steroid biosynthesis. Read about Osilodrostat

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
ISTURISA Film-coated tablet	FDA, National Drug Code (US)	MPI, US: SPL/PLR
ISTURISA Film-coated tablet	European Medicines Agency (EU)	MPI, EU: SmPC

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
H02CA02		H Systemic hormonal preparations, excl. Sex hormones and insulins → H02 Corticosteroids for systemic use → H02C Antiadrenal preparations → H02CA Anticorticosteroids
Discover more medicines within H02CA02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: EE	Ravimiamet	Identifier(s): 1809671, 1809682, 1809693
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 062005, 578438, 598411
Country: FR	Base de données publique des médicaments	Identifier(s): 61640118, 65986587, 67185086
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 396065, 396068, 396072
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 9209, 9211
Country: IT	Agenzia del Farmaco	Identifier(s): 048442014, 048442026, 048442038
Country: JP	医薬品医療機器総合機構	Identifier(s): 2499015F1026, 2499015F2022
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1089190, 1089191, 1089192
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100429970, 100429987, 100430000
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W68432001, W68433001, W68434001
Country: US	FDA, National Drug Code	Identifier(s): 55292-320, 55292-321, 55292-322