The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
H | Systemic hormonal preparations, excl. Sex hormones and insulins | |
2
|
H02 | Corticosteroids for systemic use | |
3
|
H02C | Antiadrenal preparations | |
4
|
H02CA | Anticorticosteroids | |
5
|
H02CA02 |
| Active Ingredient |
|---|
|
Osilodrostat is a cortisol synthesis inhibitor. It potently inhibits 11β-hydroxylase (CYP11B1), the enzyme responsible for the final step of cortisol biosynthesis in the adrenal gland. In Cushing’s disease, the fall in plasma cortisol concentration also stimulates ACTH secretion, via the feedback mechanism which accelerates steroid biosynthesis. |
| Document | Type | Information Source | |
|---|---|---|---|
| ISTURISA Film-coated tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| ISTURISA Film-coated tablet | MPI, EU: SmPC | European Medicines Agency (EU) |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.