KIVEXA

This brand name is authorized in Austria, Australia, Canada, Cyprus, Germany, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Ireland, Lithuania, Mexico, Netherlands, New Zealand, Poland, Romania, Singapore, United Kingdom, South Africa

Active ingredients

The drug KIVEXA contains a combination of these active pharmaceutical ingredients (APIs):

1
UNII J220T4J9Q2 - ABACAVIR SULFATE
 

Abacavir is a NRTI. It is a potent selective inhibitor of HIV-1 and HIV-2. Abacavir is metabolised intracellularly to the active moiety, carbovir 5'-triphosphate (TP). In vitro studies have demonstrated that its mechanism of action in relation to HIV is inhibition of the HIV reverse transcriptase enzyme, an event which results in chain termination and interruption of the viral replication cycle.

 
Read more about Abacavir
2
UNII 2T8Q726O95 - LAMIVUDINE
 

Lamivudine is a nucleoside analogue which has activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV). Its main mode of action is as a chain terminator of viral reverse transcription.

 
Read more about Lamivudine

Medication package inserts

Below package inserts are available for further reading:

Document Type Information Source  
 KIVEXA Film-coated tablet MPI, EU: SmPC European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group Classification
J05AR02 Lamivudine and abacavir J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AR Antivirals for treatment of HIV infections, combinations
Discover more medicines within J05AR02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
AU Pharmaceutical Benefits Scheme 10357D
CA Health Products and Food Branch 02269341
DE Bundesinstitut für Arzneimittel und Medizinprodukte 00462309, 00605571, 00910535, 01179691, 01718171, 01746345, 01973130, 02163893, 02163901, 04169730, 04911709, 04980030, 05495130, 06063958, 06560616, 06867674, 07745565, 10335428, 10335440, 11662649, 11722794, 12344472, 12575852, 13825400, 14227061, 14227078, 16529642
EC Agencia Nacional de Regulación, Control y Vigilancia Sanitaria 2931-MEE-0717
EE Ravimiamet 1198515, 1367344
ES Centro de información online de medicamentos de la AEMPS 04298002
FI Lääkealan turvallisuus- ja kehittämiskeskus 101961
FR Base de données publique des médicaments 69855489
GB Medicines & Healthcare Products Regulatory Agency 368072, 89918
HK Department of Health Drug Office 53855
LT Valstybinė vaistų kontrolės tarnyba 1029332, 1056547
MX Comisión Federal para la Protección contra Riesgos Sanitarios 479M2005
NL Z-Index G-Standaard, PRK 136050
NZ Medicines and Medical Devices Safety Authority 11560
PL Rejestru Produktów Leczniczych 100137983
RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale W65115001, W65115002
SG Health Sciences Authority 13230P
ZA Health Products Regulatory Authority A39/20.2.8/0030

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