This brand name is authorized in Ecuador
The drug LERTUS FORTE contains a combination of these active pharmaceutical ingredients (APIs):
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1
Diclofenac
UNII QTG126297Q - DICLOFENAC SODIUM
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Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E2 (PGE2) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms. |
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2
Codeine
UNII GSL05Y1MN6 - CODEINE PHOSPHATE
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Codeine is a centrally acting weak analgesic. Codeine exerts its effect through ฮผ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| M01AB55 | Diclofenac, combinations | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AB Acetic acid derivatives and related substances |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EC | Agencia Nacional de Regulaciรณn, Control y Vigilancia Sanitaria | Identifier(s): 24.116-1-11-11 |
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