This brand name is authorized in Canada, Estonia, Hong Kong, Ireland, Malta, Netherlands, New Zealand, United Kingdom, United States, South Africa
The drug LIGNOSPAN contains a combination of these active pharmaceutical ingredients (APIs):
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1
Lidocaine hydrochloride monohydrate
UNII V13007Z41A - LIDOCAINE HYDROCHLORIDE
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Lidocaine, like other local anaesthetics, causes a reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the nerve membrane. Local anaesthetics of the amide-type are thought to act within the sodium channels of the nerve membrane. |
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2
Epinephrine
UNII 30Q7KI53AK - EPINEPHRINE BITARTRATE
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Epinephrine is a direct acting sympathomimetic agent, which exerts effects on both α and β adrenoceptors. It has more pronounced effects on β than on α adrenoceptors, although α effects prevail at high doses. The effects of adrenaline include increased rate and force of cardiac contraction, cutaneous vasoconstriction and broncho-dilatation. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N01BB52 | Lidocaine, combinations | N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BB Amides |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: CA | Health Products and Food Branch | Identifier(s): 00375780, 00375799 |
| Country: EE | Ravimiamet | Identifier(s): 1807141 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 213136, 350621 |
| Country: HK | Department of Health Drug Office | Identifier(s): 21773 |
| Country: MT | Medicines Authority | Identifier(s): MA035/00101 |
| Country: NL | Z-Index G-Standaard | Identifier(s): 14785854 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 145793 |
| Country: NZ | Medicines and Medical Devices Safety Authority | Identifier(s): 2070 |
| Country: US | FDA, National Drug Code | Identifier(s): 0362-1095, 0362-1096 |
| Country: ZA | Health Products Regulatory Authority | Identifier(s): J/4/208 |
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