Chemical formula: C₁₄H₂₂N₂O Molecular mass: 234.337 g/mol PubChem compound: 3676
Lidocaine, like other local anaesthetics, causes a reversible blockade of impulse propagation along nerve fibres by preventing the inward movement of sodium ions through the nerve membrane. Local anaesthetics of the amide-type are thought to act within the sodium channels of the nerve membrane.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
C01BB01 | Lidocaine | C Cardiovascular system → C01 Cardiac therapy → C01B Antiarrhythmics, class I and III → C01BB Antiarrhythmics, class Ib |
C05AD01 | Lidocaine | C Cardiovascular system → C05 Vasoprotectives → C05A Agents for treatment of hemorrhoids and anal fissures for topical use → C05AD Local anesthetics |
D04AB01 | Lidocaine | D Dermatologicals → D04 Antipruritics, incl. antihistamines, anesthetics, etc. → D04A Antipruritics, incl. antihistamines, anesthetics, etc. → D04AB Anesthetics for topical use |
N01BB02 | Lidocaine | N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BB Amides |
R02AD02 | Lidocaine | R Respiratory system → R02 Throat preparations → R02A Throat preparations → R02AD Anesthetics, local |
S01HA07 | Lidocaine | S Sensory organs → S01 Ophthalmologicals → S01H Local anesthetics → S01HA Local anesthetics |
S02DA01 | Lidocaine | S Sensory organs → S02 Otologicals → S02D Other otologicals → S02DA Analgesics and anesthetics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
XYLOCAINE Spray | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Lidocaine is an active ingredient of these brands:
United States (US)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)
Japan (JP)Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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