MACUGEN

This brand name is authorized in United States. It is also authorized in Lithuania, Romania.

Active ingredients

The drug MACUGEN contains one active pharmaceutical ingredient (API):

1	Pegaptanib UNII 3HP012Q0FH - PEGAPTANIB SODIUM
	Pegaptanib is a pegylated modified oligonucleotide that binds with high specificity and affinity to extracellular Vascular Endothelial Growth Factor (VEGF165) inhibiting its activity. VEGF is a secreted protein that induces angiogenesis, vascular permeability and inflammation, all of which are thought to contribute to the progression of the neovascular (wet) form of AMD.
	Read more about Pegaptanib

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
MACUGEN Solution for injection	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
S01LA03	Pegaptanib	S Sensory organs → S01 Ophthalmologicals → S01L Ocular vascular disorder agents → S01LA Antineovascularisation agents
Discover more medicines within S01LA03

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
LT	Valstybinė vaistų kontrolės tarnyba	1029679
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W64998001
US	FDA, National Drug Code	68782-001