This brand name is authorized in United States
The drug MARCAINE WITH EPINEPHRINE contains a combination of these active pharmaceutical ingredients (APIs):
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1
Bupivacaine
UNII 7TQO7W3VT8 - BUPIVACAINE HYDROCHLORIDE
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Bupivacaine is an amide-type, long-acting local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. |
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2
Epinephrine
UNII 30Q7KI53AK - EPINEPHRINE BITARTRATE
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Epinephrine is a direct acting sympathomimetic agent, which exerts effects on both α and β adrenoceptors. It has more pronounced effects on β than on α adrenoceptors, although α effects prevail at high doses. The effects of adrenaline include increased rate and force of cardiac contraction, cutaneous vasoconstriction and broncho-dilatation. |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: US | FDA, National Drug Code | Identifier(s): 0409-1746, 0409-1749, 0409-1752, 0409-1755, 52584-746 |
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