This brand name is authorized in Hong Kong
The drug METOPLEX contains a combination of these active pharmaceutical ingredients (APIs):
1
Bromhexine
UNII YC2ZOM3Z8V - BROMHEXINE HYDROCHLORIDE
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Bromhexine is an expectorant used in the treatment of respiratory disorders associated with viscid or excessive mucus. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as “secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport”. |
2
Caffeine
UNII 3G6A5W338E - CAFFEINE
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Caffeine is structurally related to the methylxanthines theophylline and theobromine. Caffeine’s main action is as a CNS stimulant. |
3
Carbinoxamine
UNII 02O55696WH - CARBINOXAMINE MALEATE
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Carbinoxamine is a histamine-H1 receptor blocking agent. It is an antihistamine with anticholinergic (drying) and sedative properties. Carbinoxamine appears to compete with histamine (type H1) for receptor sites on effector cells in the gastrointestinal tract, blood vessels and respiratory tract. Carbinoxamine is effective for the symptomatic treatment of seasonal and perennial allergic rhinitis; vasomotor rhinitis; allergic conjunctivitis due to inhalant allergens and foods; mild, uncomplicated allergic skin manifestations of urticaria and angioedema; dermatographism; as therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled. |
4
Demorphan
UNII 9D2RTI9KYH - DEXTROMETHORPHAN HYDROBROMIDE
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Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors. |
5
Papaverine
UNII 23473EC6BQ - PAPAVERINE HYDROCHLORIDE
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This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
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Country: HK | Department of Health Drug Office | Identifier(s): 27787 |
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