This brand name is authorized in Nigeria
The drug MIXADIN contains a combination of these active pharmaceutical ingredients (APIs):
1
Ephedrine
UNII GN83C131XS - EPHEDRINE
|
Ephedrine is a sympathomimetic amine acting directly on the alpha and beta receptors and indirectly by increasing the release of noradrenaline by the sympathetic nerve endings. As with any sympathomimetic agent, ephedrine stimulates the central nervous system, the cardiovascular system, the respiratory system, and the sphincters of the digestive and urinary systems. |
2
Chlorphenamine
UNII 3U6IO1965U - CHLORPHENIRAMINE
|
Chlorphenamine is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorphenamine also has anticholinergic activity. |
3
Demorphan
UNII 7355X3ROTS - DEXTROMETHORPHAN
|
Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors. |
4
Guaifenesin
UNII 495W7451VQ - GUAIFENESIN
|
Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. In turn, this may increase the efficiency of the cough reflex and facilitate removal of the secretions. Guaifenesin is over-the-counter drug for the treatment of cough and common cold. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
R05FB02 | Cough suppressants and expectorants | R Respiratory system → R05 Cough and cold preparations → R05F Cough suppressants and expectorants, combinations → R05FB Other cough suppressants and expectorants |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: NG | Registered Drug Product Database | Identifier(s): 04-4088 |
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