This brand name is authorized in Ireland, Israel, Malta, New Zealand, Poland, Romania, South Africa, Turkey, UK.
The drug NUROFEN PLUS contains a combination of these active pharmaceutical ingredients (APIs):
1
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UNII
WK2XYI10QM - IBUPROFEN
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Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation. |
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2
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UNII
GSL05Y1MN6 - CODEINE PHOSPHATE
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Codeine is a centrally acting weak analgesic. Codeine exerts its effect through μ opioid receptors, although codeine has low affinity for these receptors, and its analgesic effect is due to its conversion to morphine. Codeine, particularly in combination with other analgesics such as paracetamol, has been shown to be effective in acute nociceptive pain. The anti-tussive activity of codeine is probably due to its depressant effect on the medullary cough centre in the brain. |
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Below package inserts are available for further reading:
| Document | Type | Information Source | |
|---|---|---|---|
| NUROFEN PLUS Film-coated tablet | MPI, EU: SmPC | Health Products Regulatory Authority (IE) |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC Group | Classification | |
|---|---|---|
| M01AE51 | Ibuprofen, combinations | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| GB | Medicines & Healthcare Products Regulatory Agency | 100581, 39157 |
| IL | מִשְׂרַד הַבְּרִיאוּת | 5147 |
| MT | Medicines Authority | MA1447/00101, MA1447/00105 |
| NZ | Medicines and Medical Devices Safety Authority | 11463 |
| PL | Rejestru Produktów Leczniczych | 100200049 |
| RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | W66071001, W66071002, W66071005, W66071006 |
| TR | İlaç ve Tıbbi Cihaz Kurumu | 8690570090017 |
| ZA | Health Products Regulatory Authority | 37/2.7/0666 |
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