Chemical formula: C₁₃H₁₈O₂ Molecular mass: 206.281 g/mol PubChem compound: 3672
Ibuprofen is a propionic acid derivative NSAID that has demonstrated its efficacy by inhibition of prostaglandin synthesis. In humans ibuprofen reduces inflammatory pain, swellings and fever. Furthermore, ibuprofen reversibly inhibits platelet aggregation.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C01EB16 | Ibuprofen | C Cardiovascular system → C01 Cardiac therapy → C01E Other cardiac preparations → C01EB Other cardiac preparations |
| G02CC01 | Ibuprofen | G Genito urinary system and sex hormones → G02 Other gynecologicals → G02C Other gynecologicals → G02CC Antiinflammatory products for vaginal administration |
| M01AE01 | Ibuprofen | M Musculo-skeletal system → M01 Antiinflammatory and antirheumatic products → M01A Antiinflammatory and antirheumatic products, non-steroids → M01AE Propionic acid derivatives |
| M02AA13 | Ibuprofen | M Musculo-skeletal system → M02 Topical products for joint and muscular pain → M02A Topical products for joint and muscular pain → M02AA Antiinflammatory preparations, non-steroids for topical use |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| BRUFEN 400 mg Tablet | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
| TEFIN Suppository | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
| NUROFEN DURANCE Medicated plaster | Health Products Regulatory Authority (IE) | MPI, EU: SmPC | |
| IBUPROFEN 600mg Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| PEDEA Solution for injection | European Medicines Agency (EU) | MPI, EU: SmPC | |
| IBU Tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| CALPROFEN Oral suspension | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| FENBID 10% w/w Gel | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| IBUPROFEN 400mg Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Ibuprofen is an active ingredient of these brands:
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