This brand name is authorized in South Africa
The drug ORIZIT contains a combination of these active pharmaceutical ingredients (APIs):
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1
Isoniazid
UNII V83O1VOZ8L - ISONIAZID
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Isoniazid is used mainly in the treatment of pulmonary tuberculosis but it appears to be effective also in the treatment of extrapulmonary lesions, including meningitis and genito-urinary disease. |
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2
Rifampicin
UNII VJT6J7R4TR - RIFAMPIN
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Rifampicin is an active bactericidial antituberculosis drug which is particularly active against the rapidly growing extracellular organisms and also has bactericidial activity intracellularly. Rifampicin inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| J04AM02 | Rifampicin and isoniazid | J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AM Combinations of drugs for treatment of tuberculosis |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: ZA | Health Products Regulatory Authority | Identifier(s): 51/20.2.3/0854.852 |
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