Chemical formula: C₄₃H₅₈N₄O₁₂ Molecular mass: 822.94 g/mol PubChem compound: 5381226
Rifampicin is an active bactericidial antituberculosis drug which is particularly active against the rapidly growing extracellular organisms and also has bactericidial activity intracellularly. Rifampicin inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
ATC code | Group title | Classification |
---|---|---|
J04AB02 | Rifampicin | J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AB Antibiotics |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Title | Information Source | Document Type | |
---|---|---|---|
RIFADIN Capsule | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
RIFADIN Solvent | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Rifampicin is an active ingredient of these brands:
United States (US)Brazil (BR)Canada (CA)Croatia (HR)Ecuador (EC)Estonia (EE)
Finland (FI)Hong Kong (HK)Japan (JP)Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)South Africa (ZA)
Tunisia (TN)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.