This brand name is authorized in Hong Kong, United States
The drug OSENI contains a combination of these active pharmaceutical ingredients (APIs):
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1
Alogliptin
UNII EEN99869SC - ALOGLIPTIN BENZOATE
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Alogliptin is a potent and highly selective inhibitor of DPP-4, >10,000-fold more selective for DPP-4 than other related enzymes including DPP-8 and DPP-9. Alogliptin improves glycaemic control via a glucose-dependent mechanism, whereby insulin release is enhanced and glucagon levels are suppressed when glucose levels are high. |
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2
Pioglitazone
UNII JQT35NPK6C - PIOGLITAZONE HYDROCHLORIDE
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Pioglitazone effects may be mediated by a reduction of insulin resistance. Pioglitazone appears to act via activation of specific nuclear receptors (peroxisome proliferator activated receptor gamma) leading to increased insulin sensitivity of liver, fat and skeletal muscle cells in animals. Treatment with pioglitazone has been shown to reduce hepatic glucose output and to increase peripheral glucose disposal in the case of insulin resistance. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A10BD09 | Pioglitazone and alogliptin | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BD Combinations of oral blood glucose lowering drugs |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: HK | Department of Health Drug Office | Identifier(s): 62859, 62860 |
| Country: SG | Health Sciences Authority | Identifier(s): 14929P, 14930P, 14931P, 14932P |
| Country: US | FDA, National Drug Code | Identifier(s): 64764-121, 64764-123, 64764-124, 64764-251, 64764-253, 64764-254 |
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