PEDITRACE

Zinc blocks the intestinal absorption of copper from the diet and the reabsorption of endogenously secreted copper. Zinc induces the production of metallothionein in the enterocyte, a protein that binds copper thereby preventing its transfer into the blood. The bound copper is then eliminated in the stool following desquamation of the intestinal cells.

Copper is a mineral that is found throughout the body. Copper helps the body absorb iron. It is also important for nerve function, bone growth, and to help your body use sugar. It also helps form collagen, a key part of bones and connective tissue. Copper may also act as an antioxidant, reducing free radicals that can damage cells and DNA.

Manganese is required for the synthesis of the mucopolysaccharides of cartilage, glucose utilisation, steroid biosynthesis and for the activity of pyruvate carboxylase. It is bound to arginase of the liver and activates many enzymes.

Selenium is an essential trace element. In human, selenium compounds are glutathione peroxidase and a selenium protein P found in the plasma. Deficiency of selenium has been associated with an endemic form of cardiomyopathy, Keshan disease and with Kaschin-Beck disease, an endemic osteoarthropathy which causes a severe deformity of the joints.

Sodium fluoride is indicated for the prevention of dental caries in adolescents and adults, particularly amongst patients at risk from multiple caries (coronal and/or root caries). The primary mode of the caries preventative action of fluoride is post-eruptive, i.e topical action. Systemic fluoride supplements are believed also to act mainly topically (i.e during ingestion, via saliva).

Iodine is an essential trace element in the human diet, necessary for the formation of thyroid hormones and consequently it is used in iodine deficiency and thyroid disorders. It also has antimicrobial activity.

For the prophylaxis and treatment of iodine deficiency disorders it may be given as potassium or sodium iodide, iodised oil, or potassium iodate. In the pre-operative management of hyperthyroidism iodine and iodides are used with antithyroid drugs such as carbimazole, thiamazole, or propylthiouracil.

Iodine has a powerful bactericidal action. It is also active against fungi, viruses, protozoa, cysts, and spores. Iodine is used as an antiseptic and disinfectant generally as a 2% or 2.5% solution.