Chemical formula: NaF Molecular mass: 41.988 g/mol PubChem compound: 5235
Sodium fluoride is indicated for the prevention of dental caries in adolescents and adults, particularly amongst patients at risk from multiple caries (coronal and/or root caries). The primary mode of the caries preventative action of fluoride is post-eruptive, i.e topical action. Systemic fluoride supplements are believed also to act mainly topically (i.e during ingestion, via saliva).
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A01AA01 | Sodium fluoride | A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AA Caries prophylactic agents |
| A12CD01 | Sodium fluoride | A Alimentary tract and metabolism → A12 Mineral supplements → A12C Other mineral supplements → A12CD Fluoride |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| FLUORIDE 5000 ppm Toothpaste | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Sodium fluoride is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Croatia (HR)
Ecuador (EC)
Estonia (EE)Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)Japan (JP)Malta (MT)
Netherlands (NL)New Zealand (NZ)
Poland (PL)Singapore (SG)
Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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