PENTASA

This brand name is authorized in United States. It is also authorized in Australia, Austria, Brazil, Canada, Croatia, Cyprus, Ecuador, Estonia, Finland, France, Germany, Hong Kong SAR China, Ireland, Israel, Italy, Japan, Lithuania, Malta, Mexico, Netherlands, New Zealand, Nigeria, Poland, Romania, Singapore, South Africa, Spain, Tunisia, Turkey, UK.

Active ingredients

The drug PENTASA contains one active pharmaceutical ingredient (API):

1	Mesalazine UNII 4Q81I59GXC - MESALAMINE
	Mesalazine is an aminosalicylate. The mechanism of action of mesalazine is not fully understood, but appears to have a topical anti-inflammatory effect on the colonic epithelial cells. Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase and lipoxygenase pathways, is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalazine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon.
	Read more about Mesalazine

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
PENTASA Prolonged release granules	MPI, EU: SmPC	Health Products Regulatory Authority (IE)
PENTASA Suppository	MPI, EU: SmPC	Medicines & Healthcare Products Regulatory Agency (GB)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
A07EC02	Mesalazine	A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07E Intestinal antiinflammatory agents → A07EC Aminosalicylic acid and similar agents
Discover more medicines within A07EC02

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
AU	Pharmaceutical Benefits Scheme	10254Q, 12198B, 12203G, 2214M, 2287J, 3413P, 8753Q
BR	Câmara de Regulação do Mercado de Medicamentos	521400802176419, 521400805116417, 521400806139410, 521400808141315, 521401801114310, 521401802110319, 521415070005803
CA	Health Products and Food Branch	02099683, 02153521, 02153556, 02153564, 02399466
DE	Bundesinstitut für Arzneimittel und Medizinprodukte	00565908, 00565914, 00565920, 00700967, 01296379, 01296385, 01977978, 01977984, 01977990, 01978009, 01978015, 02048465, 02051852, 02200111, 02200140, 02452491, 02452516, 02565999, 02566013, 02592660, 02593205, 02593292, 02593346, 02593441, 02648337, 02648366, 02815976, 02815982, 04034303, 04034326, 04034332, 04617080, 04617157, 06051435, 06848033, 09012720, 09012737, 09012743, 09205904, 09205910, 09234320, 09234337, 09234343, 09234366, 10020624, 11009872, 11071463, 11071486, 13423328, 13423334, 14398153, 15226980, 15292959, 15585650, 15657013, 16792612, 17203612
EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	1086-MEE-0615, 2189-MEE-0516, 5735-MAE-03-10, 5779-MAE-05-10
EE	Ravimiamet	1023815, 1023826, 1352810, 1352821, 1352832, 1352843, 1352854, 1500185, 1512795, 1730876
ES	Centro de información online de medicamentos de la AEMPS	60151, 60152, 60853, 62670, 77022, 77668, 79555
FI	Lääkealan turvallisuus- ja kehittämiskeskus	021196, 021508, 034512, 104836, 164039, 194132, 466153
FR	Base de données publique des médicaments	61951546, 62217530, 62289729, 66154593, 66357483, 69694541
GB	Medicines & Healthcare Products Regulatory Agency	137012, 147097, 147098, 176248, 195214, 26097, 28201, 283908, 32571, 368190, 373670, 373912, 376973, 379932, 379934, 38659
HK	Department of Health Drug Office	37044, 37099, 54514, 57788, 57790, 62218, 64784
HR	Agencija za lijekove i medicinske proizvode	HR-H-120226953, HR-H-282835727, HR-H-296920131, HR-H-589842039, HR-H-729224011
IE	Health Products Regulatory Authority	39004, 39066, 46820, 53496, 59080, 59560, 59657, 59690, 59700, 59705
IL	מִשְׂרַד הַבְּרִיאוּת	2824, 2895, 4142, 6869, 6966, 699, 7956
IT	Agenzia del Farmaco	027130044, 027130069
JP	医薬品医療機器総合機構	2399009D2020, 2399009F1149, 2399009F2030, 2399715J1020, 2399715X1023
LT	Valstybinė vaistų kontrolės tarnyba	1001535, 1001536, 1032894, 1032895, 1054528, 1054529, 1054530, 1057359, 1057360
MT	Medicines Authority	AA1314/00301, AA1314/00302, AA1314/00303
MX	Comisión Federal para la Protección contra Riesgos Sanitarios	063M98, 537M97, 611M2004
NG	Registered Drug Product Database	B4-9899, B4-9900, B4-9901, B4-9989
NL	Z-Index G-Standaard	14207028
NL	Z-Index G-Standaard, PRK	116882, 25178, 31860, 34215, 44334, 79820, 92673
NZ	Medicines and Medical Devices Safety Authority	12388, 14098, 17724, 5279, 5280, 5281, 5282
PL	Rejestru Produktów Leczniczych	100052287, 100052293, 100095902, 100099662, 100279186, 100279200, 100342520
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W58054001, W58055001, W58461001, W61355001, W61355002
SG	Health Sciences Authority	07740P, 07883P, 13448P, 14456P, 14479P, 15137P, 15614P
TN	Direction de la Pharmacie et du Médicament	55230210, 55230211, 5523022, 5523023, 5523024, 5523025, 5523026, 5523027, 5523028, 5523029
TR	İlaç ve Tıbbi Cihaz Kurumu	8697621030114, 8697621030596, 8697621030602, 8697621220126, 8697621220270, 8697621890138, 8697621910201
US	FDA, National Drug Code	54092-189, 54092-191
ZA	Health Products Regulatory Authority	33/11/0088, 43/11/0013, 43/11/0014, 44/11/0888, A40/11/0374