Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2021 Publisher: Ferring Ireland Ltd, United Drug House, Magna Drive, Magna Business Park, Citywest Road, Dublin 24, Ireland
Pentasa 1g Suppositories.
| Pharmaceutical Form |
|---|
|
Suppository. White to tan, spotted, oblong suppository. |
Each suppository contains mesalazine 1g.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Mesalazine |
Mesalazine is an aminosalicylate. The mechanism of action of mesalazine is not fully understood, but appears to have a topical anti-inflammatory effect on the colonic epithelial cells. Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase and lipoxygenase pathways, is increased in patients with chronic inflammatory bowel disease, and it is possible that mesalazine diminishes inflammation by blocking cyclooxygenase and inhibiting prostaglandin production in the colon. |
| List of Excipients |
|---|
|
Povidone |
Each suppository is individually packed in double aluminium foil and presented in cartons of 28 suppositories.
Ferring Ireland Ltd, United Drug House, Magna Drive, Magna Business Park, Citywest Road, Dublin 24, Ireland
PA1009/006/002
Date of first authorisation: 21 December 1992
Date of last renewal: 21 December 2007
| Drug | Countries | |
|---|---|---|
| PENTASA | Austria, Australia, Brazil, Canada, Cyprus, Germany, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Malta, Mexico, Nigeria, Netherlands, New Zealand, Poland, Romania, Singapore, Tunisia, Turkey, United Kingdom, United States, South Africa |
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