This brand name is authorized in Singapore
The drug PRAVAFEN contains a combination of these active pharmaceutical ingredients (APIs):
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1
Pravastatin
UNII 3M8608UQ61 - PRAVASTATIN SODIUM
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Pravastatin is a competitive inhibitor of 3-hydroxy–3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the early rate limiting step in cholesterol biosynthesis, and produces its lipid lowering effect in two ways. |
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2
Fenofibrate
UNII U202363UOS - FENOFIBRATE
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Fenofibrate is a fibric acid derivative whose lipid modifying effects reported in humans are mediated via activation of Peroxisome Proliferator Activated Receptor type α (PPARα). Through activation of PPARα, fenofibrate increases lipolysis and elimination of atherogenic triglyceride rich particles from plasma by activating lipoprotein lipase and reducing production of Apoprotein C-III. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| PRAVAFEN Hard capsule | Health Sciences Authority (SG) | MPI, Generic |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10BA03 | Pravastatin and fenofibrate | C Cardiovascular system → C10 Lipid modifying agents → C10B Lipid modifying agents, combinations → C10BA Combinations of various lipid modifying agents |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: SG | Health Sciences Authority | Identifier(s): 14508P |
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