Pravastatin Other names: Pravastatin sodium

Chemical formula: C₂₃H₃₆O₇  Molecular mass: 424.528 g/mol  PubChem compound: 54687

Active ingredient description

Pravastatin is a competitive inhibitor of 3-hydroxy–3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the early rate limiting step in cholesterol biosynthesis, and produces its lipid lowering effect in two ways.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
C10AA03 Pravastatin C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AA HMG CoA reductase inhibitors
Discover more medicines within C10AA03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 PRAVASTATIN SODIUM Tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 PRAVACHOL Tablet MPI, US: SPL/PLR FDA, National Drug Code (US)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 81093-37-0
DrugBank Drug: DB00175
KEGG Drug: D08410
PubChem Compound: 54687
RxNorm Ingredient: 42463
SNOMED-CT Concept: 373566006
Pravastatin (substance)
UNII Identifier: KXO2KT9N0G
PRAVASTATIN

Medicines

Pravastatin is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Singapore (SG)

  • (combination) PRAVAFEN as PRAVASTATIN SODIUM

South Africa (ZA)

Spain (ES)

Turkey (TR)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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