This brand name is authorized in France
The drug SAVARINE contains a combination of these active pharmaceutical ingredients (APIs):
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1
Proguanil
UNII R71Y86M0WT - PROGUANIL HYDROCHLORIDE
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Proguanil is an antimalarial drug and dihydrofolate reductase inhibitor. It acts like the other antifolate antimalarials by interfering with the folic-folinic acid systems and thus exerts its effect mainly at the time the nucleus is dividing. Proguanil is effective against the exoerythrocytic forms of some strains of plasmodium falciparum but it has little or no activity against the exoerythrocytic forms of p. Vivax. |
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2
Chloroquine
UNII 6E17K3343P - CHLOROQUINE PHOSPHATE
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Chloroquine binds to and alters the properties of DNA. Chloroquine also binds to ferriprotoporphyrin IX and this leads to lysis of the plasmodial membrane. In acute attacks of malaria, it interrupts erythrocytic schizogony of the parasite. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| P01BA01 | Chloroquine | P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01B Antimalarials → P01BA Aminoquinolines |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: FR | Base de données publique des médicaments | Identifier(s): 61006320 |
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