Chemical formula: C₁₈H₂₆ClN₃ Molecular mass: 319.872 g/mol PubChem compound: 2719
Chloroquine binds to and alters the properties of DNA. Chloroquine also binds to ferriprotoporphyrin IX and this leads to lysis of the plasmodial membrane. In acute attacks of malaria, it interrupts erythrocytic schizogony of the parasite.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| P01BA01 | Chloroquine | P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01B Antimalarials → P01BA Aminoquinolines |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| AVLOCLOR Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Chloroquine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)
Estonia (EE)
Germany (DE)
Mexico (MX)
Netherlands (NL)
Nigeria (NG)Poland (PL)
South Africa (ZA)Spain (ES)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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