This brand name is authorized in Tunisia
The drug SPIRAMIZOLE contains a combination of these active pharmaceutical ingredients (APIs):
1
Methronidazole
UNII 140QMO216E - METRONIDAZOLE
|
Metronidazole is an anti-infectious drug belonging to the pharmacotherapeutic group of nitroimidazole derivatives, which have effect mainly on strict anaerobes. This effect is probably caused by interaction with DNS and different metabolites. |
2
Spiramycin
UNII 71ODY0V87H - SPIRAMYCIN
|
Antibacterial antibiotic belonging to the macrolides family. Spiramycin inhibits translocation by binding to bacterial 50S ribosomal subunits with an apparent 1:1 stoichiometry. This antibiotic is a potent inhibitor of the binding to the ribosome of both donor and acceptor substrates. Spiramycin induces rapid breakdown of polyribosomes, an effect which has formerly been interpreted as occurring by normal ribosomal run-off followed by an antibiotic-induced block at or shortly after initiation of a new peptide. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
J01RA04 | Spiramycin and metronidazole | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01R Combinations of antibacterials → J01RA Combinations of antibacterials |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: TN | Direction de la Pharmacie et du Mรฉdicament | Identifier(s): 9223631 |
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