This brand name is authorized in Germany
The drug SPIRO COMP contains a combination of these active pharmaceutical ingredients (APIs):
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1
Spironolactone
UNII 27O7W4T232 - SPIRONOLACTONE
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Spironolactone, as a competitive aldosterone antagonist, increases sodium excretion whilst reducing potassium loss at the distal renal tubule. It has a gradual and prolonged action. |
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2
Furosemide
UNII 7LXU5N7ZO5 - FUROSEMIDE
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Furosemide inhibits active chloride transport in the thick ascending limb. Re-absorption of sodium, chloride from the nephron is reduced and a hypotonic or isotonic urine produced. The evidence from many experimental studies suggests that furosemide acts along the entire nephron with the exception of the distal exchange site. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03EB01 | Furosemide and potassium-sparing agents | C Cardiovascular system → C03 Diuretics → C03E Diuretics and potassium-sparing agents in combination → C03EB High-ceiling diuretics and potassium-sparing agents |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: DE | Bundesinstitut fĂźr Arzneimittel und Medizinprodukte | Identifier(s): 02424477, 02424483, 02788914, 02788920, 02788937, 07516669 |
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