This brand name is authorized in Austria, Canada, Cyprus, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Lithuania, Netherlands, Poland, Romania, Turkey, United Kingdom, United States
The drug TEPADINA contains one active pharmaceutical ingredient (API):
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1
Thiotepa
UNII 905Z5W3GKH - THIOTEPA
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Thiotepa is a polyfunctional cytotoxic agent related chemically and pharmacologically to the nitrogen mustard. The radiomimetic action of thiotepa is believed to occur through the release of ethylene imine radicals that, as in the case of irradiation therapy, disrupt the bonds of DNA, e.g. by alkylation of guanine at the N-7, breaking the linkage between the purine base and the sugar and liberating alkylated guanine. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| TEPADINA Powder for concentrate for solution for infusion | European Medicines Agency (EU) | MPI, EU: SmPC |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01AC01 | Thiotepa | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AC Ethylene imines |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: CA | Health Products and Food Branch | Identifier(s): 02462680, 02462702 |
| Country: EE | Ravimiamet | Identifier(s): 1462193, 1462205, 1845963 |
| Country: ES | Centro de información online de medicamentos de la AEMPS | Identifier(s): 10622001, 10622002 |
| Country: FI | Lääkealan turvallisuus- ja kehittämiskeskus | Identifier(s): 038822, 089079, 423204 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 60177724, 65410278 |
| Country: GB | Medicines & Healthcare Products Regulatory Agency | Identifier(s): 193118, 193124, 394052 |
| Country: HK | Department of Health Drug Office | Identifier(s): 63411, 63412 |
| Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 7761, 7762 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 039801016, 039801028, 039801030 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1053740, 1053741, 1082315, 1088470, 1092420 |
| Country: NL | Z-Index G-Standaard, PRK | Identifier(s): 94102, 94110 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100252721, 100252738 |
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W66786001, W66787001, W67921001 |
| Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8699783770396 |
| Country: US | FDA, National Drug Code | Identifier(s): 70121-1630, 70121-1631 |
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