TEPADINA

This brand name is authorized in United States. It is also authorized in Austria, Canada, Croatia, Cyprus, Estonia, Finland, France, Hong Kong SAR China, Ireland, Israel, Italy, Lithuania, Netherlands, Poland, Romania, Spain, Turkey, UK.

Active ingredients

The drug TEPADINA contains one active pharmaceutical ingredient (API):

1	Thiotepa UNII 905Z5W3GKH - THIOTEPA
	Thiotepa is a polyfunctional cytotoxic agent related chemically and pharmacologically to the nitrogen mustard. The radiomimetic action of thiotepa is believed to occur through the release of ethylene imine radicals that, as in the case of irradiation therapy, disrupt the bonds of DNA, e.g. by alkylation of guanine at the N-7, breaking the linkage between the purine base and the sugar and liberating alkylated guanine.
	Read more about Thiotepa

Medication package inserts

Below package inserts are available for further reading:

Document	Type	Information Source
TEPADINA Powder for concentrate for solution for infusion	MPI, EU: SmPC	European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group		Classification
L01AC01	Thiotepa	L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AC Ethylene imines
Discover more medicines within L01AC01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
CA	Health Products and Food Branch	02462680, 02462702
EE	Ravimiamet	1462193, 1462205, 1845963
ES	Centro de información online de medicamentos de la AEMPS	10622001, 10622002
FI	Lääkealan turvallisuus- ja kehittämiskeskus	038822, 089079, 423204
FR	Base de données publique des médicaments	60177724, 65410278
GB	Medicines & Healthcare Products Regulatory Agency	193118, 193124, 394052
HK	Department of Health Drug Office	63411, 63412
IL	מִשְׂרַד הַבְּרִיאוּת	7761, 7762
IT	Agenzia del Farmaco	039801016, 039801028, 039801030
LT	Valstybinė vaistų kontrolės tarnyba	1053740, 1053741, 1082315, 1088470, 1092420
NL	Z-Index G-Standaard, PRK	94102, 94110
PL	Rejestru Produktów Leczniczych	100252721, 100252738
RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	W66786001, W66787001, W67921001
TR	İlaç ve Tıbbi Cihaz Kurumu	8699783770396
US	FDA, National Drug Code	70121-1630, 70121-1631