This brand name is authorized in Ecuador
The drug TUSSOLVINA FORTE contains a combination of these active pharmaceutical ingredients (APIs):
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1
Chlorphenamine
UNII V1Q0O9OJ9Z - CHLORPHENIRAMINE MALEATE
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Chlorphenamine is a potent antihistamine (H1-antagonist). Antihistamines diminish or abolish the actions of histamine in the body by competitive reversible blockade of histamine H1-receptor sites on tissues. Chlorphenamine also has anticholinergic activity. |
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2
Guaifenesin
UNII 495W7451VQ - GUAIFENESIN
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Guaifenesin is an expectorant the action of which promotes or facilitates the removal of secretions from the respiratory tract. The precise mechanism of action of guaifenesin is not known; however, it is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. In turn, this may increase the efficiency of the cough reflex and facilitate removal of the secretions. Guaifenesin is over-the-counter drug for the treatment of cough and common cold. |
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3
Demorphan
UNII 9D2RTI9KYH - DEXTROMETHORPHAN HYDROBROMIDE
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Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R05FA02 | Opium derivatives and expectorants | R Respiratory system → R05 Cough and cold preparations → R05F Cough suppressants and expectorants, combinations → R05FA Opium derivatives and expectorants |
| R05FB02 | Cough suppressants and expectorants | R Respiratory system → R05 Cough and cold preparations → R05F Cough suppressants and expectorants, combinations → R05FB Other cough suppressants and expectorants |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EC | Agencia Nacional de Regulación, Control y Vigilancia Sanitaria | Identifier(s): 2665-MEN-0520, 6166-MAN-07-11, 650-MEN-0216 |
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