This brand name is authorized in Canada, Israel, United Kingdom, United States
The drug WELIREG contains one active pharmaceutical ingredient (API):
1
Belzutifan
UNII 7K28NB895L - BELZUTIFAN
|
Belzutifan is an inhibitor of hypoxia-inducible factor 2 alpha (HIF-2α). Belzutifan binds to HIF-2α, and in conditions of hypoxia or impairment of VHL protein function, belzutifan blocks the HIF-2α-HIF-1β interaction, leading to reduced transcription and expression of HIF-2α target genes. In vivo, belzutifan demonstrated anti-tumor activity in mouse xenograft models of renal cell carcinoma. |
Below package inserts are available for further reading:
Title | Information Source | Document Type | |
---|---|---|---|
WELIREG Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC code | Group title | Classification |
---|---|---|
L01XX74 | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
---|---|---|
Country: CA | Health Products and Food Branch | Identifier(s): 02528908 |
Country: IL | מִשְׂרַד הַבְּרִיאוּת | Identifier(s): 9270 |
Country: US | FDA, National Drug Code | Identifier(s): 0006-5331 |
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