This brand name is authorized in Japan
The drug ZACRAS contains a combination of these active pharmaceutical ingredients (APIs):
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1
Azilsartan medoxomil
UNII F9NUX55P23 - AZILSARTAN
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Azilsartan medoxomil is an orally active prodrug that is rapidly converted to the active moiety, azilsartan, which selectively antagonises the effects of angiotensin II by blocking its binding to the AT1 receptor in multiple tissues. Angiotensin II is the principal pressor agent of the RAAS, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium. |
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2
Amlodipine
UNII 864V2Q084H - AMLODIPINE BESYLATE
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Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: JP | 医薬品医療機器総合機構 | Identifier(s): 2149121F1021, 2149121F2028 |
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