ZERIT

This brand name is authorized in Estonia, Ireland, Lithuania, Netherlands, Poland, Romania.

Active ingredients

The drug ZERIT contains one active pharmaceutical ingredient (API):

1
UNII BO9LE4QFZF - STAVUDINE
 

Stavudine, a thymidine analogue, is phosphorylated by cellular kinases to stavudine triphosphate which inhibits HIV reverse transcriptase by competing with the natural substrate, thymidine triphosphate. It also inhibits viral DNA synthesis by causing DNA chain termination due to a lack of the 3'-hydroxyl group necessary for DNA elongation. Cellular DNA polymerase γ is also sensitive to inhibition by stavudine triphosphate, while cellular polymerases α and β are inhibited at concentrations 4,000-fold and 40-fold higher, respectively, than that needed to inhibit HIV reverse transcriptase.

 
Read more about Stavudine

Medication package inserts

Below package inserts are available for further reading:

Document Type Information Source  
 ZERIT Hard capsule MPI, EU: SmPC European Medicines Agency (EU)
 ZERIT Powder for oral solution MPI, EU: SmPC European Medicines Agency (EU)

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC Group Classification
J05AF04 Stavudine J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
Discover more medicines within J05AF04

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
EE Ravimiamet 1032400, 1032411, 1032422, 1032433, 1032444, 1073472, 1073528, 1073539, 1073540
LT Valstybinė vaistų kontrolės tarnyba 1015967, 1015968, 1015969, 1015970, 1015971, 1015972, 1015973, 1015974, 1015975
NL Z-Index G-Standaard, PRK 44776
PL Rejestru Produktów Leczniczych 100000480, 100000965, 100082963, 100083098, 100084092
RO Agenția Națională a Medicamentului și a Dispozitivelor Medicale W52738001

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