Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.
Language | Translation |
---|---|
English | Cystic fibrosis |
French | Fibrose kystique |
Level | Code | Title | |
---|---|---|---|
1 | IV | Endocrine, nutritional and metabolic diseases | |
2 | E70-E90 | Metabolic disorders | |
3 | E84 | Cystic fibrosis |
Code | Title | |
---|---|---|
E84.0 | Cystic fibrosis with pulmonary manifestations | |
E84.1 | Cystic fibrosis with intestinal manifestations | |
E84.8 | Cystic fibrosis with other manifestations | |
E84.9 | Cystic fibrosis, unspecified |
Active Ingredient | Description | |
---|---|---|
Dornase alfa |
Recombinant human DNase is a genetically engineered version of a naturally occurring human enzyme which cleaves extracellular DNA. In vitro, dornase alfa hydrolyses DNA in sputum and greatly reduces the viscoelasticity of cystic fibrosis sputum. |
|
Ivacaftor |
Ivacaftor is a potentiator of the CFTR protein, i.e., in vitro ivacaftor increases CFTR channel gating to enhance chloride transport in specified gating mutations with reduced channel-open probability compared to normal CFTR. Ivacaftor also potentiated the channel-open probability of R117H-CFTR, which has both low channel-open probability (gating) and reduced channel current amplitude (conductance). |
|
Mannitol |
Mannitol is a naturally occurring sugar alcohol used clinically primarily for its osmotic diuretic properties. |