Specific codes in ICD-10 are unique alphanumeric designations used to identify and categorize diseases, disorders, and conditions. They consist of 3-5 characters, including both letters and numbers, that provide a high level of detail and specificity.
| Language | Translation |
|---|---|
English
|
Toxic effect: Cyanides |
French
|
Effet toxique des cyanures |
| Level | Code | Title | |
|---|---|---|---|
| 1 | XIX | Injury, poisoning and certain other consequences of external causes | |
| 2 | T51-T65 | Toxic effects of substances chiefly nonmedicinal as to source | |
| 3 | T65 | Toxic effect of other and unspecified substances | |
| 4 | T65.0 | Toxic effect: Cyanides |
| Active Ingredient | Description | |
|---|---|---|
| Thiosulfate |
Sodium thiosulfate is indicated for sequential use with sodium nitrite for the treatment of acute cyanide poisoning that is judged to be life-threatening. The primary route of endogenous cyanide detoxification is by enzymatic transulfuration to thiocyanate (SCN-), which is relatively nontoxic and readily excreted in the urine. Sodium thiosulfate is also indicated for the prevention of ototoxicity induced by cisplatin chemotherapy. The mechanism of protection against ototoxicity may include increasing levels of endogenous antioxidants, inhibition of intracellular oxidative stress, and direct interaction between cisplatin and the thiol group in sodium thiosulfate to produce inactive platinum species. |
