Mild to moderate persistent asthma

Active Ingredient: Mometasone

Indication for Mometasone

Population group: only adults (18 years old or older)

For this indication, competent medicine agencies globally authorize below treatments:

200-400 micrograms once daily

Route of admnistration

Respiratory (Inhalation)

Defined daily dose

200 - 400 ug

Dosage regimen

From 200 To 400 ug once every day

Detailed description

The recommended starting dose for most of these patients is 400 micrograms once daily. Data suggest that better asthma control is achieved if once daily dosing is administered in the evening. Some patients may be more adequately controlled on 400 micrograms daily, given in two divided doses (200 micrograms twice daily).

The dose of mometasone 200 micrograms should be individualised and titrated to the lowest dose at which effective control of asthma is maintained. Dose reduction to 200 micrograms once daily given in the evening may be an effective maintenance dose for some patients.

Criteria

Mild asthma: symptoms >1 time a week but <1 time per day; exacerbations may affect activity and sleep; night-time asthma symptoms >2 times a month; PEF or FEV1 >80% predicted, variability 20–30%.

Moderate asthma: symptoms daily; exacerbations affect activity and sleep; night-time asthma symptoms >1 time a week; daily use of short-acting beta2 –agonist; PEF or FEV1 >60 - <80% predicted, variability >30%.

Dosage considerations

Should be administered in the evening.

Active ingredient

Mometasone

Mometasone is a topical glucocorticoid with local anti-inflammatory properties. It is likely that much of the mechanism for the effects of mometasone lies in its ability to inhibit the release of mediators of the inflammatory cascade.

Read more about Mometasone

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