Infections caused by susceptible microorganisms

Active Ingredient: Sultamicillin

Indication for Sultamicillin

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

For the treatment of the following infections caused by susceptible microorganisms:

  • Upper respiratory tract infections including sinusitis, otitis media, epiglottitis, and tonsillitis
  • Lower respiratory tract infections including bacterial pneumonia and bronchitis
  • Urinary tract infections including pyelonephritis
  • Intraabdominal infections including peritonitis, cholecystitis, endometritis, and pelvic cellulitis
  • Bacterial septicemia
  • Skin and skin structure infections
  • Bone and joint infections

As step down treatment for infections due to susceptible organisms, initially given antimicrobial therapy, particularly parenteral ampicillin-sulbactam.

For this indication, competent medicine agencies globally authorize below treatments:

750 mg twice daily

For:

Dosage regimens

Oral, 750 milligrams sultamicillin, 2 times daily, over the duration of 5 to 14 days.

Detailed description

Usual dose in adults is 750 mg twice daily.

Usual Duration of Treatment: 5 to 14 days which may be extended depending
on the type and severity of infection.

1.5-3 g every 6 hours

For:

Dosage regimens

Intravenous, between 1.5 grams sultamicillin and 3 grams sultamicillin, daily, 4 doses in total.

Detailed description

The recommended dosage of sultamicillin is 1.5 g (1 g ampicillin as the sodium salt plus 0.5 g sulbactam as the sodium salt) to 3 g (2 g ampicillin as the sodium salt plus 1 g sulbactam as the sodium salt) every six hours. This 1.5 to 3 g range represents the total of ampicillin content plus the sulbactam content of sultamicillin, and corresponds to a range of 1 g ampicillin/0.5 g sulbactam to 2 g ampicillin/1 g sulbactam. The total dose of sulbactam should not exceed 4 grams per day.

Active ingredient

Sultamicillin

Sultamicillin is the tosylate salt of the double ester of sulbactam plus ampicillin. Sulbactam is a semisynthetic beta-lactamase inhibitor which, in combination with ampicillin, extends the antibacterial activity of the latter to include some beta-lactamase-producing strains of bacteria that would otherwise be resistant.

Read more about Sultamicillin

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