Hypertensive crisis

Active Ingredient: Clonidine

Indication for Clonidine

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

For this indication, competent medicine agencies globally authorize below treatments:

150-300 ug repeated up to a maximum of 750 ug in 24 h

For:

Dosage regimens

Intravenous, between 150 micrograms clonidine and 300 micrograms clonidine, 1 to 5 times daily, over the duration of 1 day. The maximum allowed total dose is 750 micrograms clonidine daily.

Detailed description

In hypertensive crises 150 to 300 micrograms should be given by slow intravenous injection. This dose may be repeated up to a maximum of 750 micrograms in a 24 hour period.

Patients undergoing anaesthesia should continue their clonidine treatment before, during and after anaesthesia using oral or intravenous administration according to individual circumstances.

Intravenous injection of clonidine should be given slowly over 10–15 minutes to avoid a possible transient pressor effect.

Active ingredient

Clonidine

Clonidine has been shown to have both central and peripheral sites of action. With long-term treatment clonidine reduces the responsiveness of peripheral vessels to vasoconstrictor and vasodilator substances and to sympathetic nerve stimulation. Early in treatment, however, blood pressure reduction is associated with a central reduction of sympathetic outflow and increased vagal tone.

Read more about Clonidine

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