Active Ingredient: Fluvastatin
For this indication, competent medicine agencies globally authorize below treatments:
Oral
20 - 80 mg
From 10 To 40 mg 2 time(s) per day every day
Prior to initiating treatment with fluvastatin, patients should be placed on a standard cholesterol-lowering diet, which should be continued during treatment.
Starting and maintenance doses should be individualized according to the baseline LDL-C levels and the treatment goal to be accomplished.
Prior to initiating treatment with fluvastatin in children and adolescents aged 9 years and older with heterozygous familial hypercholesterolaemia, the patient should be placed on a standard cholesterol-lowering diet, and continued during treatment.
The recommended starting dose is one 20 mg capsule. Dose adjustments should be made at 6-week intervals. Doses should be individualised according to baseline LDL-C levels and the recommended goal of therapy to be accomplished. The maximum daily dose administered is 80 mg either as immediate-release capsules 40 mg twice daily or as one 80 mg prolonged-release tablet once daily.
The use of fluvastatin in combination with nicotinic acid, cholestyramine, or fibrates in children and adolescents has not been investigated.
Fluvastatin has only been investigated in children of 9 years and older with heterozygous familial hypercholesterolaemia.
It can be taken with or without meals and should be swallowed as whole with a glass of water.
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