Chemical formula: C₂₄H₂₆FNO₄ Molecular mass: 411.473 g/mol PubChem compound: 1548972
Fluvastatin, a fully synthetic cholesterol-lowering agent, is a competitive inhibitor of HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate, a precursor of sterols, including cholesterol. Fluvastatin reduces total-C, LDL-C, Apo B, and triglycerides, and increases HDL-C in patients with hypercholesterolaemia and mixed dyslipidaemia.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C10AA04 | Fluvastatin | C Cardiovascular system → C10 Lipid modifying agents → C10A Lipid modifying agents, plain → C10AA HMG CoA reductase inhibitors |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LESCOL XL Extended-release tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| FLUVASTATIN Capsules | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Fluvastatin is an active ingredient of these brands:
United States (US)
Australia (AU)
Austria (AT)
Canada (CA)
Cyprus (CY)
Estonia (EE)
Finland (FI)
France (FR)
Ireland (IE)
Lithuania (LT)
Malta (MT)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)Spain (ES)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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