Transthyretin-mediated amyloidosis (ATTR-CM)

Active Ingredient: Acoramidis

Indication for Acoramidis

Population group: only adults (18 years old or older)
Therapeutic intent: Curative procedure

Acoramidis is indicated for the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

For this indication, competent medicine agencies globally authorize below treatments:

712 mg twice daily

For:

Dosage regimens

Oral, 712 milligrams acoramidis, 2 times daily.

Detailed description

The recommended dosage of acoramidis is 712 mg orally twice daily.

Dosage considerations

With or without food.

Active ingredient

Acoramidis

Acoramidis is a selective stabilizer of transthyretin (TTR). Acoramidis binds TTR at thyroxine binding sites and slows dissociation of the TTR tetramer into its constituent monomers, the rate-limiting step in amyloidogenesis.

Read more about Acoramidis

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