Chemical formula: C₁₅H₁₇FN₂O₃ Molecular mass: 292.122 g/mol PubChem compound: 71464713
Acoramidis is a selective stabilizer of transthyretin (TTR). Acoramidis binds TTR at thyroxine binding sites and slows dissociation of the TTR tetramer into its constituent monomers, the rate-limiting step in amyloidogenesis.
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ATTRUBY Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Acoramidis is an active ingredient of these brands:
United States (US)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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